Atosiban acetate
CAS No. 914453-95-5
Atosiban acetate ( RW22164;RWJ22164 )
产品货号. M19935 CAS No. 914453-95-5
Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥543 | 有现货 |
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10MG | ¥948 | 有现货 |
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25MG | ¥1442 | 有现货 |
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50MG | ¥1758 | 有现货 |
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100MG | ¥2284 | 有现货 |
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500MG | ¥5630 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Atosiban acetate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor.
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产品描述Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result there is reduced release of intracellular stored calcium from the sarcoplasmic reticulum of myometrial cells and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor atosiban at the recommended dosage antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence.
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同义词RW22164;RWJ22164
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others
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适应症Preterm labour
化学信息
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CAS Number914453-95-5
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分子量1054.24
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分子式C45H71N11O14S2
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESCC(O)=O.CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Akerlund M et al. The effect on the human uterus of two newly developed competitive inhibitors of oxytocin and vasopressin. Acta Obstet Gynecol Scand. 1985;64(6):499-504.
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