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Atosiban acetate

CAS No. 914453-95-5

Atosiban acetate ( RW22164;RWJ22164 )

产品货号. M19935 CAS No. 914453-95-5

Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥543 有现货
10MG ¥948 有现货
25MG ¥1442 有现货
50MG ¥1758 有现货
100MG ¥2284 有现货
500MG ¥5630 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Atosiban acetate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor.
  • 产品描述
    Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result there is reduced release of intracellular stored calcium from the sarcoplasmic reticulum of myometrial cells and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor atosiban at the recommended dosage antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence.
  • 同义词
    RW22164;RWJ22164
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Others
  • 适应症
    Preterm labour

化学信息

  • CAS Number
    914453-95-5
  • 分子量
    1054.24
  • 分子式
    C45H71N11O14S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    CC(O)=O.CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Akerlund M et al. The effect on the human uterus of two newly developed competitive inhibitors of oxytocin and vasopressin. Acta Obstet Gynecol Scand. 1985;64(6):499-504.
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